One goal of the multi-decade multi-billion-dollar restoration of the Florida Everglades is to recreate hydrologic conditions in Everglades National Park (ENP) associated with pulses of aquatic animal prey production that support large colonies of seasonally nesting wading birds. Southern Florida has been invaded by several non-indigenous predatory tropical fishes and while some remain restricted to anthropogenic canals, others invade the native wetlands. Recent studies indicate that establishment of the Asian Swamp Eel (Monopterus albus/javanensis) has disrupted the hydrology-mediated production of crayfish and some small fishes in the SE wetlands of ENP (circa 2012). A long-term monitoring dataset was used to document population responses, and in this talk we present a complete community dataset of fish and decapods to quantify changes to the diversity, composition, and biomass of prey produced for wading birds in Taylor Slough (ENP). After the establishment of swamp eels in Taylor Slough the fish and decapod richness declined by 25% and communities shifted to a novel composition dominated by grass shrimp and a few species of relatively small-bodied fishes. Swamp eels disproportionately reduced the biomass of wading bird prey taxa; while there has been a 68% decline in total small fish and decapod biomass, the biomass of the primary prey species for nesting wading birds declined by 80%. If similar impacts follow the spread of swamp eels into other major drainages of the Everglades, the invasion may precipitate an ecosystem collapse – simplifying and restructuring the aquatic communities of a vast world heritage wetland and limiting the trophic support for wading bird aggregations that are important indicators for ecological restoration. Swamp eel invasions are occurring in tropical and warm temperate aquatic systems beyond the Everglades. Their continuous global introductions and spread should be a concern for freshwater conservation of benthic decapods, other large crawling macroinvertebrates and small benthic fishes.