As climate change progresses, stream networks will increasingly face frequent and intense droughts that co-occur with rising temperatures. It is widely hypothesized that drought undermines ecosystem stability by simplifying communities, rewiring food webs, and altering microbially-mediated nutrient cycling. However, an alternative hypothesis suggests that warming may trigger thermal compensatory responses at the individual, community, and ecosystem level, which may enhance ecosystem resilience to drought. For example, warming may favor resilient taxa, such as desiccation-resistant N₂-fixing cyanobacteria that tolerate higher temperatures. When dried, cyanobacteria become the dominant persisting biomass, allowing rapid recovery of net ecosystem production and nutrient demand upon rewetting. However, the effect of warming on ecosystem nutrient cycling response and recovery to drying remains largely unstudied. We outline a large-scale drought manipulation study that will test whether warming amplifies or reduces the response of key nutrient cycling processes, including biological nutrient uptake, N₂-fixation, and denitrification, to drying in streams. We hypothesize that warming will shorten response time and accelerate recovery of nutrient cycling. We will employ a network of six streams with similar water chemistry but differing temperatures (6oC–24oC) within the Hengill Geothermal Catchment, Iceland, alongside outdoor stream mesocosms (ambient and warmed; n = 8 of each) at the University of Birmingham, United Kingdom. We will impose a summer-long drought in the Icelandic streams via water diversion, and a month-long drought in our stream mesocosms initiated by gradual flow reduction. Before and after drying, we will quantify nutrient (nitrate [NO₃⁻], ammonium [NH₄⁺], and phosphate [PO4⁻]) uptake metrics, including uptake velocity (vf, mm/min) and areal uptake (U, µmol/m2/hr), and N₂-flux (representing potential N₂-fixation vs. denitrification). The findings of our study will inform predictions about the response of nutrient cycling to interacting rising temperatures and drought in freshwater ecosystems under global climate change.